Role of bladder-report imaging and the data system in predicting muscle-invasive bladder cancer: a diagnostic meta-analysis

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Int J Urol. December 19, 2021. doi: 10.1111 / iju.14748. Online ahead of print.


The objective of this study is to systematically assess the diagnostic performance of the Vesical Imaging-Reporting and Data System for predicting muscle-invasive bladder cancer. Embase, PubMed, and Web of Science were searched from September 1, 2018 to July 30, 2021 to include the appropriate studies. We included studies that included bladder imaging, reporting, and data system data and their associated pathological findings, and assessed their quality using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. . Pooled sensitivity and specificity were calculated and plotted using a hierarchical summary receptor operating characteristic modeling. Meta-regression analysis was performed to detect heterogeneity. A total of 20 studies with 2725 patients were included. When the cut-off point was 3, the combined sensitivity and specificity were 0.92 (0.89-0.94) and 0.85 (0.78-0.90), respectively, and 0.82 (0.75-0.88) and 0.95 (0.91-0.97), respectively, when the cut-off point was 4. The area under the curve was 0.95 and 0.95 , respectively. The heterogeneity was substantially considerable in sensitivity and specificity. All variables in the subgroup, including number of patients, study design, magnetic resonance imaging field strength, number of radiologists, surgical design, diffusion-weighted imaging, and contrast enhanced dynamic magnetic resonance imaging contributed to the heterogeneity of sensitivity when the cut-off point was 3 and the heterogeneity of specificity when the cut-off point was 4. The acquisition plan d Multiple images of the diffusion-weighted imaging achieved higher sensitivity than the single-image acquisition plane of the diffusion-weighted imaging in bladder imaging and data system groups 3 and 4, and higher specificity in the Vesical Imaging-Reporting and Data System 4 group. Another important source of heterogeneity was the cut-off point. The diagnostic performance of the Vesical Imaging-Reporting and Data System for predicting muscle invasive bladder cancer was excellent at the two cut-off points of the Vesical Imaging-Reporting and Data System 3 and 4. Several image acquisition shots Diffusion-weighted imaging should more attention in the bladder imaging and data system.

PMID: 34923686 | DOI: 10.1111 / iju.14748

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